ACSM1

Across TCGA patient cohorts, ACSM1 mutation is significantly associated with the RNA expression of many other genes, with 4,132 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACSM1-associated genes across cancer lineages are DCLRE1A, SAAL1, and WDR62. Each is linked with ACSM1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ACSM1-to-partner and partner-to-ACSM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCLRE1A grouped by ACSM1-low versus ACSM1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSM1→partner) and Y-score (partner→ACSM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DCLRE1A →	+0.346	+2.087	.009	.005	3	4
UCEC	SAAL1 →	+0.464	+4.010	<.001	<.001	3	4
UCEC	WDR62 →	+0.527	+2.606	<.001	<.001	3	4
UCEC	FH →	+0.483	+3.180	<.001	<.001	3	4
SKCM	EIF2B2 →	+0.347	+1.540	<.001	<.001	3	4
UCEC	PSMC3IP →	+0.536	+1.711	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,132 associations by consensus.

DCLRE1A by ACSM1 expression — UCEC

Explore this box plot interactively →