ACSM1

Across TCGA cell cohorts, ACSM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,864 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACSM1-associated GO terms across cancer lineages are Positive regulation of iron ion transport, Positive regulation of iron ion transmembrane transport, and Purine ribonucleoside metabolic process. Each is linked with ACSM1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ACSM1-to-partner and partner-to-ACSM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of iron ion transport grouped by ACSM1-low versus ACSM1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSM1→partner) and Y-score (partner→ACSM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Positive regulation of iron ion transport →	+1.260	+0.048	<.001	.003	3	9
SKIN	Positive regulation of iron ion transmembrane transport →	+1.260	+0.048	<.001	.003	3	9
LARGE_INTESTINE	Purine ribonucleoside metabolic process →	-0.119	-0.181	.002	.005	3	8
BREAST	Positive regulation of endothelial cell development →	+0.217	+0.437	.001	.007	3	8
BREAST	Positive regulation of establishment of endothelial barrier →	+0.217	+0.437	.001	.007	3	8
LUNG_NSCLC_LUSC	Maintenance of blood-brain barrier →	+0.210	+0.173	.001	.008	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,864 associations by consensus.

Positive regulation of iron ion transport by ACSM1 expression — SKIN

Explore this box plot interactively →