ACSL6

Across TCGA cell cohorts, ACSL6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,955 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACSL6-associated GO terms across cancer lineages are Mitochondrial electron transport, NADH to ubiquinone, Purine ribonucleoside triphosphate metabolic process, and Ribonucleoside triphosphate biosynthetic process. Each is linked with ACSL6 in more than 9 cancer types. Because this analysis shows association rather than direction, both ACSL6-to-partner and partner-to-ACSL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, NADH to ubiquinone grouped by ACSL6-low versus ACSL6-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSL6→partner) and Y-score (partner→ACSL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Mitochondrial electron transport, NADH to ubiquinone →	+0.076	+0.510	<.001	<.001	3	9
SKIN	Purine ribonucleoside triphosphate metabolic process →	+0.098	+0.686	<.001	<.001	3	9
SKIN	Ribonucleoside triphosphate biosynthetic process →	+0.060	+0.380	<.001	.001	3	9
BLOOD_Leukemia	Proton motive force-driven ATP synthesis →	+0.075	+0.511	<.001	.005	1	10
BLOOD_Leukemia	Proton motive force-driven mitochondrial ATP synthesis →	+0.069	+0.628	<.001	.001	2	9
SKIN	Negative regulation of syncytium formation by plasma membrane fusion →	+0.104	+0.520	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,955 associations by consensus.

Mitochondrial electron transport, NADH to ubiquinone by ACSL6 expression — SKIN

Explore this box plot interactively →