ACSL6

Across TCGA cell cohorts, ACSL6 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible ACSL6-associated genes across cancer lineages are PRLHR, WFDC12, and TEX48. Each is linked with ACSL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACSL6-to-partner and partner-to-ACSL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRLHR grouped by ACSL6-low versus ACSL6-high in KIDNEY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSL6→partner) and Y-score (partner→ACSL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	PRLHR →	+0.030	+5.000	<.001	.005	3	1
KIDNEY	WFDC12 →	+0.066	+5.000	<.001	.005	3	1
KIDNEY	TEX48 →	+0.133	+5.000	<.001	.005	3	1
OESOPHAGUS	ANKRD30BL →	+0.023	+4.906	<.001	.006	3	1
OESOPHAGUS	DEFB4A →	+0.653	+4.906	<.001	.006	3	1
LARGE_INTESTINE	OR10W1 →	+0.010	+3.562	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

PRLHR by ACSL6 expression — KIDNEY

Explore this box plot interactively →