Across TCGA patient cohorts, ACSL5 mutation is significantly associated with the RNA expression of many other genes, with 1,294 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACSL5-associated genes across cancer lineages are RPS14P7, IMMP1L, and OXSM. Each is linked with ACSL5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACSL5-to-partner and partner-to-ACSL5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSL5→partner) and Y-score (partner→ACSL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPS14P7 →	+0.054	+4.424	.001	.008	3	3
UCEC	IMMP1L →	+0.358	+2.595	.009	<.001	3	2
UCEC	OXSM →	+0.323	+2.173	.004	.009	3	2
UCEC	SEC13 →	+0.412	+3.741	<.001	<.001	3	2
UCEC	DFFA →	+0.414	+3.332	.003	.005	3	2
UCEC	NSA2 →	+0.408	+3.708	.009	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,294 associations by consensus.

Exploration

ACSL5 survival (RNA) · tumor vs normal (RNA) · all ACSL5 data types