Across TCGA patient cohorts, ACSL5 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACSL5-associated genes across cancer lineages are p62 Lck ligand, Annexin-1, and 14-3-3_beta. Each is linked with ACSL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACSL5-to-partner and partner-to-ACSL5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSL5→partner) and Y-score (partner→ACSL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.390	+2.415	.002	.003	3	2
UCEC	Annexin-1 →	+0.566	+3.169	.007	.018	3	2
UCEC	14-3-3_beta →	-0.086	-2.295	.034	.033	3	1
UCEC	MEK1 →	+0.465	+2.415	.001	.003	3	1
UCEC	Notch1 →	+0.166	+2.013	.003	.016	3	1
UCEC	STAT3_pY705 →	-0.386	-1.906	<.001	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

ACSL5 survival (RNA) · tumor vs normal (RNA) · all ACSL5 data types