Across TCGA cell cohorts, ACSL5 mutation is significantly associated with the mutation status of many other genes, with 1,630 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACSL5-associated genes across cancer lineages are COL14A1, UBR2, and FAM160A2. Each is linked with ACSL5 in more than 4 cancer types. Because this analysis shows association rather than direction, both ACSL5-to-partner and partner-to-ACSL5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSL5→partner) and Y-score (partner→ACSL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	COL14A1 →	+5.502	+5.502	.003	.003	1	5
BREAST	UBR2 →	+4.297	+4.857	.009	.009	1	3
BREAST	FAM160A2 →	+4.297	+4.857	.009	.009	1	3
LARGE_INTESTINE	HELZ →	+2.459	+3.321	.005	.005	1	3
LARGE_INTESTINE	PCDHA4 →	+2.459	+3.321	.005	.005	1	3
LARGE_INTESTINE	SH2D3C →	+2.080	+3.906	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,630 associations by consensus.

Exploration

ACSL5 survival (RNA) · tumor vs normal (RNA) · all ACSL5 data types