ACSL3

Across TCGA patient cohorts, ACSL3 mutation is significantly associated with the RNA expression of many other genes, with 2,907 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACSL3-associated genes across cancer lineages are BNIP3P41, UBFD1P1, and DHRS11. Each is linked with ACSL3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACSL3-to-partner and partner-to-ACSL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3P41 grouped by ACSL3-low versus ACSL3-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSL3→partner) and Y-score (partner→ACSL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	BNIP3P41 →	+0.048	+3.450	.001	.008	3	3
SKCM	UBFD1P1 →	+0.034	+5.039	<.001	<.001	3	2
UCEC	DHRS11 →	+0.503	+3.617	<.001	.001	3	2
UCEC	SEPTIN14P12 →	+0.218	+2.220	.004	.001	3	2
BLCA	USP9YP2 →	+0.039	+7.640	<.001	.009	3	2
UCEC	RNA5SP436 →	+0.232	+2.414	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,907 associations by consensus.

BNIP3P41 by ACSL3 expression — STAD

Explore this box plot interactively →