ACSL1

Across TCGA patient cohorts, ACSL1 mutation is significantly associated with the RNA expression of many other genes, with 3,050 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACSL1-associated genes across cancer lineages are MIR7-3, GCC1, and DCP1A. Each is linked with ACSL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACSL1-to-partner and partner-to-ACSL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7-3 grouped by ACSL1-low versus ACSL1-high in OV.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSL1→partner) and Y-score (partner→ACSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MIR7-3 →	+0.200	+4.572	.001	.008	3	3
UCEC	GCC1 →	+0.427	+2.058	.001	<.001	3	3
UCEC	DCP1A →	+0.454	+1.777	.001	.002	3	2
UCEC	TAF9 →	+0.532	+2.523	<.001	<.001	3	2
UCEC	C8orf89 →	-0.309	-2.658	<.001	<.001	3	2
UCEC	TUBGCP5 →	+0.358	+1.809	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,050 associations by consensus.

MIR7-3 by ACSL1 expression — OV

Explore this box plot interactively →