ACSF3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ACSF3 mutation is significantly associated with the RNA expression of many other genes, with 2,594 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACSF3-associated genes across cancer lineages are RN7SL392P, RNU6-252P, and RNU6-99P. Each is linked with ACSF3 in more than 3 cancer types. Because this analysis shows association rather than direction, both ACSF3-to-partner and partner-to-ACSF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL392P grouped by ACSF3-low versus ACSF3-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSF3→partner) and Y-score (partner→ACSF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADRN7SL392P →+0.442+4.084<.001.00534
STADRNU6-252P →+1.006+4.167<.001.00433
LUSCRNU6-99P →+1.063+7.924<.001.00833
LUSCRNU6-622P →+1.088+7.924<.001.00833
STADMIR519A1 →+1.226+4.031<.001.00533
STADRPL35AP18 →+0.197+4.330.006.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,594 associations by consensus.

RN7SL392P by ACSF3 expression — STAD

Box plot of RN7SL392P in ACSF3-low vs ACSF3-high samples in STAD.

Explore this box plot interactively →

Exploration