ACSF3

Across TCGA cell cohorts, ACSF3 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACSF3-associated genes across cancer lineages are OR11H2, AVP, and USP26. Each is linked with ACSF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACSF3-to-partner and partner-to-ACSF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H2 grouped by ACSF3-low versus ACSF3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSF3→partner) and Y-score (partner→ACSF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR11H2 →	+0.024	+4.927	.001	.001	3	2
LARGE_INTESTINE	AVP →	+0.041	+3.217	<.001	.006	3	1
LARGE_INTESTINE	USP26 →	+0.045	+3.836	.005	.003	3	1
LARGE_INTESTINE	MDGA2 →	+0.153	+3.176	<.001	.003	3	1
LARGE_INTESTINE	BPIFB6 →	+0.014	+3.700	<.001	.009	3	1
LARGE_INTESTINE	LIPK →	+0.205	+3.817	<.001	.002	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

OR11H2 by ACSF3 expression — BLOOD_Lymphoma

Explore this box plot interactively →