ACRV1

Across TCGA patient cohorts, ACRV1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,216 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACRV1-associated genes across cancer lineages are NCAPH, MYBL2, and ABCA6. Each is linked with ACRV1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ACRV1-to-partner and partner-to-ACRV1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACRV1 versus NCAPH in BRCA, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACRV1→partner) and Y-score (partner→ACRV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NCAPH →	+0.990	+0.382	<.001	<.001	3	8
BRCA	MYBL2 →	+1.524	+0.421	<.001	<.001	3	7
LSCC	ABCA6 →	-0.809	-0.302	<.001	<.001	3	7
LSCC	WDR43 →	+0.735	+0.331	<.001	<.001	3	7
LSCC	POLR1C →	+0.649	+0.206	<.001	<.001	3	7
LSCC	ALG3 →	+0.813	+0.300	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,216 associations by consensus.

ACRV1 vs NCAPH — BRCA

Explore this scatter interactively →