ACRV1

Across TCGA cell cohorts, ACRV1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,745 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACRV1-associated GO terms across cancer lineages are Positive regulation of chromosome organization, Centriole assembly, and Microtubule organizing center organization. Each is linked with ACRV1 in more than 15 cancer types. Because this analysis shows association rather than direction, both ACRV1-to-partner and partner-to-ACRV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome organization grouped by ACRV1-low versus ACRV1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACRV1→partner) and Y-score (partner→ACRV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Positive regulation of chromosome organization →	+0.059	+0.203	<.001	<.001	2	16
KIDNEY	Centriole assembly →	+0.070	+0.144	.005	.005	3	14
LARGE_INTESTINE	Microtubule organizing center organization →	+0.074	+0.197	<.001	.001	3	14
LARGE_INTESTINE	Centrosome cycle →	+0.077	+0.206	<.001	<.001	3	14
CNS	Mitotic sister chromatid segregation →	+0.090	+0.190	<.001	<.001	3	14
BLOOD_Lymphoma	Chromosome segregation →	+0.083	+0.278	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,745 associations by consensus.

Positive regulation of chromosome organization by ACRV1 expression — SKIN

Explore this box plot interactively →