ACR

Across TCGA cell cohorts, ACR RNA expression is significantly associated with the go_rna of many other GO terms, with 1,543 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ACR-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with ACR in more than 6 cancer types. Because this analysis shows association rather than direction, both ACR-to-partner and partner-to-ACR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by ACR-low versus ACR-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACR→partner) and Y-score (partner→ACR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of myoblast fusion →	+0.109	+0.221	<.001	.003	3	7
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.124	+0.185	.002	.002	3	7
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.113	+0.202	.002	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Locomotory exploration behavior →	+0.152	+0.226	.003	.008	3	7
STOMACH	Negative regulation of myoblast fusion →	+0.122	+0.171	.003	.007	3	7
STOMACH	Negative regulation of transcription by RNA polymerase III →	+0.112	+0.107	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,543 associations by consensus.

Regulation of myoblast fusion by ACR expression — LUNG_SCLC

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