Across TCGA patient cohorts, ACP7 protein abundance is significantly associated with the RNA expression of many other genes, with 767 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ACP7-associated genes across cancer lineages are PLA2G3, SLC5A1, and ESRP2. Each is linked with ACP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACP7-to-partner and partner-to-ACP7 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACP7→partner) and Y-score (partner→ACP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PLA2G3 →	+2.150	+1.711	<.001	<.001	3	1
HNSC	SLC5A1 →	+2.451	+1.880	<.001	<.001	3	1
HNSC	ESRP2 →	+0.769	+1.175	.002	.001	3	1
HNSC	GABPB1 →	-0.500	-0.958	.003	.009	3	1
HNSC	KLC3 →	+0.830	+1.168	<.001	.001	3	1
HNSC	EBI3 →	-1.086	-1.203	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 767 associations by consensus.

Exploration

ACP7 survival (RNA) · tumor vs normal (RNA) · all ACP7 data types