Across TCGA patient cohorts, ACP7 mutation is significantly associated with the RNA expression of many other genes, with 1,716 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACP7-associated genes across cancer lineages are KIAA0930, SNX8, and BRAT1. Each is linked with ACP7 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACP7-to-partner and partner-to-ACP7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACP7→partner) and Y-score (partner→ACP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIAA0930 →	+0.429	+2.716	.001	.003	3	3
UCEC	SNX8 →	+0.431	+2.823	.004	.001	3	3
SKCM	BRAT1 →	+0.434	+3.472	.005	.002	3	3
SKCM	PSMC3IP →	+0.590	+2.472	<.001	.001	3	3
SKCM	ATP2A1-AS1 →	+0.746	+3.469	<.001	.002	3	2
SKCM	RN7SL383P →	+0.037	+3.723	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,716 associations by consensus.

Exploration

ACP7 survival (RNA) · tumor vs normal (RNA) · all ACP7 data types