ACP5

Across TCGA patient cohorts, ACP5 protein abundance is significantly associated with the RNA expression of many other genes, with 7,865 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACP5-associated genes across cancer lineages are SIRPB1, HTRA4, and CCL18. Each is linked with ACP5 in more than 7 cancer types. Because this analysis shows association rather than direction, both ACP5-to-partner and partner-to-ACP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACP5 versus SIRPB1 in UCEC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACP5→partner) and Y-score (partner→ACP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SIRPB1 →	+0.689	+0.438	.001	<.001	3	8
UCEC	HTRA4 →	+1.070	+0.543	<.001	<.001	3	8
CCRCC	CCL18 →	+2.570	+0.732	<.001	<.001	3	8
UCEC	NCF2 →	+1.088	+0.517	<.001	<.001	3	7
GBM	CCRL2 →	+0.826	+0.610	.001	<.001	3	7
UCEC	APOC1 →	+1.695	+0.533	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,865 associations by consensus.

ACP5 vs SIRPB1 — UCEC

Explore this scatter interactively →