ACP5

Across TCGA cell cohorts, ACP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,247 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ACP5-associated GO terms across cancer lineages are Positive regulation of proteolysis, Regulation of macroautophagy, and Endosome organization. Each is linked with ACP5 in more than 7 cancer types. Because this analysis shows association rather than direction, both ACP5-to-partner and partner-to-ACP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of proteolysis grouped by ACP5-low versus ACP5-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACP5→partner) and Y-score (partner→ACP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of proteolysis →	+0.089	+1.240	.002	.001	3	8
BLOOD_Leukemia	Regulation of macroautophagy →	+0.028	+0.903	<.001	.002	3	8
PANCREAS	Endosome organization →	+0.048	+1.300	.001	.001	3	8
BREAST	Negative regulation of intrinsic apoptotic signaling pathway →	+0.085	+1.352	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Regulation of tolerance induction dependent upon immune response →	+0.964	+1.229	.001	.002	3	7
BREAST	Regulation of intrinsic apoptotic signaling pathway →	+0.066	+1.225	.003	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,247 associations by consensus.

Positive regulation of proteolysis by ACP5 expression — PANCREAS

Explore this box plot interactively →