ACP5

Across TCGA cell cohorts, ACP5 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACP5-associated genes across cancer lineages are MORN5, GUCA2A, and FAM24A. Each is linked with ACP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACP5-to-partner and partner-to-ACP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MORN5 grouped by ACP5-low versus ACP5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACP5→partner) and Y-score (partner→ACP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MORN5 →	+0.166	+3.855	.001	.007	3	1
BLOOD_Leukemia	GUCA2A →	+0.031	+4.384	<.001	.006	3	1
BLOOD_Leukemia	FAM24A →	+0.051	+4.384	<.001	.006	3	1
BLOOD_Leukemia	TSSK1B →	+0.011	+3.874	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MORN5 by ACP5 expression — BLOOD_Leukemia

Explore this box plot interactively →