ACP2

Across TCGA cell cohorts, ACP2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ACP2-associated genes across cancer lineages are MTNR1B, CCL19, and PNLIPRP1. Each is linked with ACP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACP2-to-partner and partner-to-ACP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTNR1B grouped by ACP2-low versus ACP2-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACP2→partner) and Y-score (partner→ACP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	MTNR1B →	+0.188	+4.029	<.001	.009	3	1
OVARY	CCL19 →	+0.071	+4.029	<.001	.009	3	1
OVARY	PNLIPRP1 →	+0.031	+4.450	<.001	.004	3	1
OVARY	SCGB1D4 →	+0.097	+4.807	<.001	.003	3	1
LARGE_INTESTINE	ACSM6 →	+0.027	+4.169	<.001	.007	3	1
LARGE_INTESTINE	CFHR2 →	+0.046	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MTNR1B by ACP2 expression — OVARY

Explore this box plot interactively →