ACP1

Across TCGA pan-cancer cohorts, ACP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ACP1 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ACP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ACP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

HNSC, PDAC, and LSCC are the cancer types where ACP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	0.924	1.000	.037	18	view →
PDAC	OS	Quartile	III,IV	0.520	0.953	.004	15	view →
LSCC	DFS	Quartile	III,IV	0.705	0.980	.020	9	view →
CCRCC	OS	Tertile	IV	1.000	0.173	.049	4	view →
GBM	DFS	Median	All	0.652	0.837	.012	4	view →
LUAD	OS	Median	III,IV	0.232	0.710	.020	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ACP1–HNSC (DFS)

Open the HNSC breakdown →