ACP1

Across TCGA patient cohorts, ACP1 mutation is significantly associated with the RNA expression of many other genes, with 145 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ACP1-associated genes across cancer lineages are MIR1256, RNA5SP419, and RNA5SP414. Each is linked with ACP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACP1-to-partner and partner-to-ACP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1256 grouped by ACP1-low versus ACP1-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACP1→partner) and Y-score (partner→ACP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	MIR1256 →	+0.296	+4.721	<.001	.007	3	2
UCEC	RNA5SP419 →	+0.866	+2.755	<.001	.009	3	2
UCEC	RNA5SP414 →	+0.683	+2.933	<.001	.006	3	2
SKCM	RPS12P15 →	+0.104	+3.076	<.001	.005	3	2
PRAD	OR7E129P →	+0.051	+4.490	<.001	.009	3	1
PRAD	SCGB1C1 →	+0.308	+4.304	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 145 associations by consensus.

MIR1256 by ACP1 expression — PRAD

Explore this box plot interactively →