ACOX2

Across TCGA patient cohorts, ACOX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,753 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACOX2-associated proteins across cancer lineages are PRKAR2A, DNAJA1_S335, and FYCO1. Each is linked with ACOX2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ACOX2-to-partner and partner-to-ACOX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACOX2 versus PRKAR2A in BRCA, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOX2→partner) and Y-score (partner→ACOX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PRKAR2A →	+0.264	+1.298	<.001	<.001	3	6
BRCA	DNAJA1_S335 →	-0.971	-1.901	<.001	<.001	3	6
BRCA	FYCO1 →	+0.494	+1.523	<.001	<.001	3	6
OV	MPI →	+0.467	+0.893	<.001	<.001	3	6
OV	NPEPL1 →	+0.445	+0.832	.003	<.001	3	5
BRCA	PARVA →	+0.534	+1.585	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,753 associations by consensus.

ACOX2 vs PRKAR2A — BRCA

Explore this scatter interactively →