ACOX2

Across TCGA patient cohorts, ACOX2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,402 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACOX2-associated genes across cancer lineages are FAM72B, PRR11, and UTP4. Each is linked with ACOX2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ACOX2-to-partner and partner-to-ACOX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACOX2 versus FAM72B in BRCA, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOX2→partner) and Y-score (partner→ACOX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM72B →	-0.660	-0.570	.008	.005	3	5
BRCA	PRR11 →	-0.896	-0.444	.006	.007	3	5
LSCC	UTP4 →	-0.484	-0.321	<.001	<.001	3	4
LSCC	C18orf54 →	-0.693	-0.338	.002	<.001	3	4
GBM	UBE2SP1 →	-0.409	-0.393	.004	.002	3	4
GBM	CENPF →	-1.000	-0.524	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,402 associations by consensus.

ACOX2 vs FAM72B — BRCA

Explore this scatter interactively →