ACOX1

Across TCGA cell cohorts, ACOX1 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ACOX1-associated genes across cancer lineages are OR51B2, LRCH2, and CBLIF. Each is linked with ACOX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACOX1-to-partner and partner-to-ACOX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51B2 grouped by ACOX1-low versus ACOX1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOX1→partner) and Y-score (partner→ACOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR51B2 →	+0.360	+3.854	<.001	.006	3	2
BLOOD_Lymphoma	LRCH2 →	+0.477	+3.857	<.001	.003	3	1
BLOOD_Lymphoma	CBLIF →	+0.069	+3.192	<.001	.008	3	1
BLOOD_Lymphoma	TDRD5 →	+0.463	+3.491	<.001	.009	3	1
BLOOD_Lymphoma	CALHM4 →	+0.259	+3.765	<.001	.001	3	1
BLOOD_Lymphoma	VCX2 →	+1.040	+3.459	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

OR51B2 by ACOX1 expression — SKIN

Explore this box plot interactively →