ACOT9

Across TCGA patient cohorts, ACOT9 protein abundance is significantly associated with the RNA expression of many other genes, with 13,240 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ACOT9-associated genes across cancer lineages are SRPX2, THEM6, and RPA1. Each is linked with ACOT9 in more than 3 cancer types. Because this analysis shows association rather than direction, both ACOT9-to-partner and partner-to-ACOT9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACOT9 versus SRPX2 in COAD, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOT9→partner) and Y-score (partner→ACOT9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SRPX2 →	+1.265	+0.329	<.001	<.001	3	4
HNSC	THEM6 →	-0.920	-0.184	.001	<.001	3	4
BRCA	RPA1 →	-0.689	-0.467	.001	.003	3	4
LSCC	GINS4 →	-1.039	-0.310	<.001	<.001	3	4
COAD	MED14 →	+0.531	+0.215	.002	.005	3	4
COAD	SRSF3 →	-0.570	-0.285	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,240 associations by consensus.

ACOT9 vs SRPX2 — COAD

Explore this scatter interactively →