ACOT9

Across TCGA patient cohorts, ACOT9 mutation is significantly associated with the RNA expression of many other genes, with 1,946 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACOT9-associated genes across cancer lineages are OR4F15, OR51A1P, and ZNRF2P3. Each is linked with ACOT9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACOT9-to-partner and partner-to-ACOT9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F15 grouped by ACOT9-low versus ACOT9-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOT9→partner) and Y-score (partner→ACOT9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OR4F15 →	+0.033	+5.303	<.001	.006	3	2
COAD	OR51A1P →	+0.093	+6.142	.001	<.001	3	2
SKCM	ZNRF2P3 →	+0.127	+5.037	<.001	.009	3	2
SKCM	CDY7P →	+0.034	+5.292	<.001	.006	3	2
UCEC	MIR1183 →	+0.268	+1.956	.002	.004	3	2
UCEC	RNA5SP369 →	+0.273	+1.831	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,946 associations by consensus.

OR4F15 by ACOT9 expression — HNSC

Explore this box plot interactively →