ACOT9

Across TCGA cell cohorts, ACOT9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,172 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ACOT9-associated GO terms across cancer lineages are Type 2 mitophagy, Positive regulation of actin filament bundle assembly, and Regulation of focal adhesion assembly. Each is linked with ACOT9 in more than 11 cancer types. Because this analysis shows association rather than direction, both ACOT9-to-partner and partner-to-ACOT9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Type 2 mitophagy grouped by ACOT9-low versus ACOT9-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOT9→partner) and Y-score (partner→ACOT9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Type 2 mitophagy →	+0.266	+1.519	.002	<.001	2	12
BONE	Positive regulation of actin filament bundle assembly →	+0.183	+1.121	<.001	<.001	3	11
BONE	Regulation of focal adhesion assembly →	+0.150	+0.876	<.001	<.001	3	11
BREAST	Regulation of glutamate uptake involved in transmission of nerve impulse →	+0.156	+0.982	.003	.006	3	11
BONE	Regulation of cell-substrate junction assembly →	+0.150	+0.876	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Negative regulation of Rho protein signal transduction →	+0.156	+1.196	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,172 associations by consensus.

Type 2 mitophagy by ACOT9 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →