ACOT4

Across TCGA cell cohorts, ACOT4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,179 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ACOT4-associated GO terms across cancer lineages are Protein catabolic process at synapse, Protein catabolic process at postsynapse, and Regulation of epinephrine secretion. Each is linked with ACOT4 in more than 11 cancer types. Because this analysis shows association rather than direction, both ACOT4-to-partner and partner-to-ACOT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein catabolic process at synapse grouped by ACOT4-low versus ACOT4-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOT4→partner) and Y-score (partner→ACOT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Protein catabolic process at synapse →	+0.144	+0.672	<.001	<.001	3	12
BLOOD_Leukemia	Protein catabolic process at postsynapse →	+0.144	+0.672	<.001	<.001	3	12
PANCREAS	Regulation of epinephrine secretion →	-1.064	-0.970	.002	.002	3	11
LUNG_NSCLC_LUSC	Positive regulation of microtubule depolymerization →	-0.158	-0.696	.003	.008	3	8
LUNG_NSCLC_LUSC	Negative regulation of epinephrine secretion →	-1.398	-1.099	.001	.005	2	9
PANCREAS	Negative regulation of leukocyte tethering or rolling →	+1.208	+0.908	.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,179 associations by consensus.

Protein catabolic process at synapse by ACOT4 expression — BLOOD_Leukemia

Explore this box plot interactively →