ACOT13

Across TCGA patient cohorts, ACOT13 protein abundance is significantly associated with the RNA expression of many other genes, with 9,475 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ACOT13-associated genes across cancer lineages are FCGR3B, CEACAM3, and FPR2. Each is linked with ACOT13 in more than 5 cancer types. Because this analysis shows association rather than direction, both ACOT13-to-partner and partner-to-ACOT13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACOT13 versus FCGR3B in LSCC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOT13→partner) and Y-score (partner→ACOT13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FCGR3B →	-1.486	-0.454	<.001	<.001	3	6
HNSC	CEACAM3 →	-0.740	-0.605	<.001	<.001	3	6
COAD	FPR2 →	-1.323	-0.670	<.001	<.001	3	6
PDAC	ADGRE3 →	-0.878	-0.646	<.001	<.001	3	5
PDAC	CXCR2 →	-1.172	-0.841	<.001	<.001	3	5
COAD	CSF3R →	-1.078	-0.519	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,475 associations by consensus.

ACOT13 vs FCGR3B — LSCC

Explore this scatter interactively →