ACOT12

Across TCGA patient cohorts, ACOT12 protein abundance is significantly associated with the RNA expression of many other genes, with 647 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ACOT12-associated genes across cancer lineages are RBM23, DICER1, and CPPED1. Each is linked with ACOT12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACOT12-to-partner and partner-to-ACOT12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACOT12 versus RBM23 in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOT12→partner) and Y-score (partner→ACOT12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RBM23 →	+0.668	+1.096	.002	.001	3	1
BRCA	DICER1 →	+1.508	+1.035	.002	.002	3	1
BRCA	CPPED1 →	+1.139	+0.772	.005	.006	3	1
BRCA	SYT17 →	+2.125	+1.385	<.001	.008	3	1
BRCA	TMC5 →	+3.290	+0.745	<.001	.009	3	1
BRCA	LILRA1 →	+0.573	+1.350	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 647 associations by consensus.

ACOT12 vs RBM23 — BRCA

Explore this scatter interactively →