ACOT12

Across TCGA cell cohorts, ACOT12 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,593 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACOT12-associated GO terms across cancer lineages are Autophagosome organization, Autophagosome assembly, and Protein localization to non-motile cilium. Each is linked with ACOT12 in more than 4 cancer types. Because this analysis shows association rather than direction, both ACOT12-to-partner and partner-to-ACOT12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagosome organization grouped by ACOT12-low versus ACOT12-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOT12→partner) and Y-score (partner→ACOT12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Autophagosome organization →	+0.035	+0.096	<.001	.001	3	5
BLOOD_Leukemia	Autophagosome assembly →	+0.037	+0.110	<.001	<.001	3	5
BREAST	Protein localization to non-motile cilium →	+0.064	+0.110	.002	.007	3	4
BLOOD_Leukemia	Positive regulation of natural killer cell mediated immune response to tumor cell →	-1.050	-0.151	<.001	<.001	3	4
BLOOD_Leukemia	Positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target →	-0.817	-0.134	<.001	.002	3	4
BLOOD_Leukemia	Adiponectin-activated signaling pathway →	+0.065	+0.130	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,593 associations by consensus.

Autophagosome organization by ACOT12 expression — BLOOD_Leukemia

Explore this box plot interactively →