ACOT11

Across TCGA cell cohorts, ACOT11 mutation is significantly associated with the RNA expression of many other genes, with 98 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACOT11-associated genes across cancer lineages are OR52K1, LY6G6F, and SOD2. Each is linked with ACOT11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACOT11-to-partner and partner-to-ACOT11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52K1 grouped by ACOT11-low versus ACOT11-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOT11→partner) and Y-score (partner→ACOT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OR52K1 →	+0.006	+5.087	<.001	.004	3	1
URINARY_TRACT	LY6G6F →	+0.040	+5.087	<.001	.004	3	1
LARGE_INTESTINE	SOD2 →	+0.772	+3.212	.004	.006	3	1
LARGE_INTESTINE	MUC5B →	+1.725	+3.212	.001	.006	3	1
LARGE_INTESTINE	GALNT8 →	+0.896	+3.212	.002	.006	3	1
LARGE_INTESTINE	TNFRSF11A →	+2.070	+3.212	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 98 associations by consensus.

OR52K1 by ACOT11 expression — URINARY_TRACT

Explore this box plot interactively →