ACOD1

Across TCGA patient cohorts, ACOD1 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ACOD1-associated genes across cancer lineages are GAPDHP30, OR5D3P, and IFNA1. Each is linked with ACOD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACOD1-to-partner and partner-to-ACOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDHP30 grouped by ACOD1-low versus ACOD1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOD1→partner) and Y-score (partner→ACOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GAPDHP30 →	+0.323	+4.577	<.001	.004	3	1
COAD	OR5D3P →	+0.084	+5.917	<.001	.001	3	1
COAD	IFNA1 →	+0.111	+4.681	.004	.003	3	1
COAD	MIR147A →	+0.617	+4.893	<.001	.005	3	1
COAD	TRDJ2 →	+0.983	+4.384	.001	.006	3	1
COAD	TRDJ3 →	+1.094	+4.951	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

GAPDHP30 by ACOD1 expression — COAD

Explore this box plot interactively →