ACOD1

Across TCGA cell cohorts, ACOD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 93 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACOD1-associated GO terms across cancer lineages are Respiratory burst after phagocytosis, Enucleate erythrocyte differentiation, and Regulation of mitochondrion organization. Each is linked with ACOD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACOD1-to-partner and partner-to-ACOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Respiratory burst after phagocytosis grouped by ACOD1-low versus ACOD1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACOD1→partner) and Y-score (partner→ACOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Respiratory burst after phagocytosis →	-0.189	-0.002	.003	.005	3	3
BONE	Enucleate erythrocyte differentiation →	-0.184	-0.005	<.001	.007	3	2
BLOOD_Leukemia	Regulation of mitochondrion organization →	+0.039	+0.002	.005	.004	3	2
BLOOD_Leukemia	Regulation of extrinsic apoptotic signaling pathway via death domain receptors →	+0.082	+0.001	.003	.009	2	3
BLOOD_Leukemia	Positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity →	+0.082	+0.001	.004	.009	3	2
BLOOD_Leukemia	Response to pain →	+0.082	+0.001	.008	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 93 associations by consensus.

Respiratory burst after phagocytosis by ACOD1 expression — BLOOD_Leukemia

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