ACKR2

Across TCGA cell cohorts, ACKR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,283 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ACKR2-associated GO terms across cancer lineages are Viral process, Phospholipid biosynthetic process, and Lysosomal lumen acidification. Each is linked with ACKR2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ACKR2-to-partner and partner-to-ACKR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral process grouped by ACKR2-low versus ACKR2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACKR2→partner) and Y-score (partner→ACKR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Viral process →	+0.076	+1.012	<.001	.008	3	10
KIDNEY	Phospholipid biosynthetic process →	+0.040	+0.111	.008	<.001	3	8
OVARY	Lysosomal lumen acidification →	+0.126	+1.694	<.001	.007	3	8
URINARY_TRACT	Cellular response to indole-3-methanol →	+0.185	+2.000	<.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of macroautophagy →	+0.055	+0.387	<.001	.001	3	8
STOMACH	Viral life cycle →	+0.095	+1.068	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,283 associations by consensus.

Viral process by ACKR2 expression — STOMACH

Explore this box plot interactively →