Across TCGA cell cohorts, ACKR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,884 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACKR1-associated GO terms across cancer lineages are Cellular response to type I interferon, Purine nucleoside triphosphate biosynthetic process, and Purine ribonucleoside triphosphate biosynthetic process. Each is linked with ACKR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ACKR1-to-partner and partner-to-ACKR1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACKR1→partner) and Y-score (partner→ACKR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Cellular response to type I interferon →	+0.062	+0.719	<.001	.003	3	6
LUNG_NSCLC_LUAD	Purine nucleoside triphosphate biosynthetic process →	+0.059	+0.047	.001	.009	3	5
LUNG_NSCLC_LUAD	Purine ribonucleoside triphosphate biosynthetic process →	+0.059	+0.047	.001	.009	3	5
LUNG_NSCLC_LUAD	Aerobic electron transport chain →	+0.067	+0.061	<.001	.007	3	5
LUNG_NSCLC_LUAD	ATP synthesis coupled electron transport →	+0.064	+0.049	<.001	.006	3	5
LUNG_NSCLC_LUAD	Mitochondrial ATP synthesis coupled electron transport →	+0.064	+0.049	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,884 associations by consensus.

Exploration

ACKR1 survival (RNA) · tumor vs normal (RNA) · all ACKR1 data types