ACHE

Across TCGA patient cohorts, ACHE RNA expression is significantly associated with the protein abundance of many other proteins, with 9,682 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ACHE-associated proteins across cancer lineages are TRIM2, PPP1R12B, and PXDN. Each is linked with ACHE in more than 2 cancer types. Because this analysis shows association rather than direction, both ACHE-to-partner and partner-to-ACHE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACHE versus TRIM2 in LUAD, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACHE→partner) and Y-score (partner→ACHE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TRIM2 →	+0.516	+0.944	<.001	.006	3	3
HNSC	PPP1R12B →	+0.835	+1.098	<.001	<.001	3	3
CCRCC	PXDN →	-0.367	-0.702	.008	.005	3	3
HNSC	XIRP1 →	+1.528	+1.086	<.001	<.001	3	3
HNSC	BIN1 →	+0.878	+0.809	<.001	<.001	3	3
UCEC	COL14A1_T1676 →	+1.052	+0.593	.004	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,682 associations by consensus.

ACHE vs TRIM2 — LUAD

Explore this scatter interactively →