ACER2

Across TCGA patient cohorts, ACER2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,941 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ACER2-associated proteins across cancer lineages are NPM1_S254, NUP153_T699, and PGAM1_S31. Each is linked with ACER2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ACER2-to-partner and partner-to-ACER2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACER2 versus NPM1_S254 in BRCA, with a Pearson correlation of -0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACER2→partner) and Y-score (partner→ACER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NPM1_S254 →	-1.054	-0.650	<.001	<.001	3	5
BRCA	NUP153_T699 →	-0.825	-1.040	<.001	<.001	3	5
BRCA	PGAM1_S31 →	-0.578	-1.315	<.001	<.001	3	4
BRCA	PHC3 →	+0.293	+0.704	<.001	<.001	3	4
BRCA	PURA →	+0.338	+0.834	<.001	<.001	3	4
LUAD	IPO5 →	-0.262	-0.731	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,941 associations by consensus.

ACER2 vs NPM1_S254 — BRCA

Explore this scatter interactively →