ACER2

Across TCGA cell cohorts, ACER2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,990 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACER2-associated GO terms across cancer lineages are Copper ion export, Positive regulation of mRNA catabolic process, and Glycerophospholipid biosynthetic process. Each is linked with ACER2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ACER2-to-partner and partner-to-ACER2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion export grouped by ACER2-low versus ACER2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACER2→partner) and Y-score (partner→ACER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Copper ion export →	-0.171	-0.443	<.001	<.001	3	10
KIDNEY	Positive regulation of mRNA catabolic process →	+0.076	+1.123	<.001	<.001	3	10
URINARY_TRACT	Glycerophospholipid biosynthetic process →	+0.056	+2.547	<.001	<.001	3	10
URINARY_TRACT	Phospholipid biosynthetic process →	+0.056	+2.910	<.001	<.001	3	9
STOMACH	Negative regulation of supramolecular fiber organization →	+0.085	+1.631	<.001	<.001	3	9
PANCREAS	Regulation of myoblast differentiation →	+0.082	+1.469	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,990 associations by consensus.

Copper ion export by ACER2 expression — BLOOD_Leukemia

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