ACER1

Across TCGA patient cohorts, ACER1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,135 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible ACER1-associated GO terms across cancer lineages are Ruffle organization, Positive regulation of autophagy, and Negative regulation of protein-containing complex assembly. Each is linked with ACER1 in more than 16 cancer types. Because this analysis shows association rather than direction, both ACER1-to-partner and partner-to-ACER1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ruffle organization grouped by ACER1-low versus ACER1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACER1→partner) and Y-score (partner→ACER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Ruffle organization →	+0.108	+0.428	<.001	<.001	3	17
STAD	Positive regulation of autophagy →	+0.070	+0.272	<.001	<.001	3	17
STAD	Negative regulation of protein-containing complex assembly →	+0.062	+0.269	<.001	<.001	3	17
STAD	Regulation of chemotaxis →	+0.091	+0.394	<.001	<.001	3	16
ESCA	Regulation of epithelial cell differentiation →	+0.048	+0.690	<.001	.001	3	16
STAD	Lymphocyte homeostasis →	+0.075	+0.212	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,135 associations by consensus.

Ruffle organization by ACER1 expression — STAD

Explore this box plot interactively →