ACE2

Across TCGA cell cohorts, ACE2 mutation is significantly associated with the drug of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACE2-associated genes across cancer lineages are GSK429286A and CDK9_5038. Each is linked with ACE2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACE2-to-partner and partner-to-ACE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK429286A grouped by ACE2-low versus ACE2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACE2→partner) and Y-score (partner→ACE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK429286A →	+0.315	+2.652	.044	.045	3	1
LARGE_INTESTINE	CDK9_5038 →	+0.635	+2.906	.020	.033	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GSK429286A by ACE2 expression — LARGE_INTESTINE

Explore this box plot interactively →