ACD

Across TCGA patient cohorts, ACD mutation is significantly associated with the immune_cell of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACD-associated genes across cancer lineages are MPP, Pericytes, and CMP. Each is linked with ACD in more than 1 cancer types. Because this analysis shows association rather than direction, both ACD-to-partner and partner-to-ACD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by ACD-low versus ACD-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACD→partner) and Y-score (partner→ACD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MPP →	+0.014	+2.140	.049	.028	3	2
HNSC	Pericytes →	+0.057	+3.949	.002	.014	3	1
BLCA	CMP →	+0.033	+3.074	.028	.025	3	1
BLCA	MEP →	+0.032	+2.828	.043	.036	3	1
BLCA	Osteoblast →	+0.056	+2.773	.004	.011	3	1
SKCM	Hepatocytes →	-0.012	-1.913	.019	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

MPP by ACD expression — COAD

Explore this box plot interactively →