ACBD7

Across TCGA patient cohorts, ACBD7 mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible ACBD7-associated genes across cancer lineages are RPL36AP48, HNRNPA1P72, and LINC02727. Each is linked with ACBD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACBD7-to-partner and partner-to-ACBD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL36AP48 grouped by ACBD7-low versus ACBD7-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACBD7→partner) and Y-score (partner→ACBD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL36AP48 →	+0.208	+3.822	.008	.005	3	2
BLCA	HNRNPA1P72 →	+0.061	+4.639	.001	<.001	3	1
BLCA	LINC02727 →	+0.054	+4.289	<.001	.007	3	1
BLCA	ATP5PDP1 →	+0.113	+4.049	.004	.003	3	1
BLCA	SLC25A51P2 →	+0.041	+4.147	<.001	.009	3	1
BLCA	OR1AC1P →	+0.443	+4.444	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

RPL36AP48 by ACBD7 expression — SKCM

Explore this box plot interactively →