ACBD4

Across TCGA patient cohorts, ACBD4 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACBD4-associated genes across cancer lineages are Annexin_VII, Myosin-IIa, and p21. Each is linked with ACBD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACBD4-to-partner and partner-to-ACBD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin_VII grouped by ACBD4-low versus ACBD4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACBD4→partner) and Y-score (partner→ACBD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin_VII →	-0.148	-2.459	.027	.020	3	2
UCEC	Myosin-IIa →	+0.207	+3.329	.033	.005	3	1
UCEC	p21 →	+0.260	+2.820	.005	.035	3	1
UCEC	p62 Lck ligand →	+0.461	+3.584	.003	.002	3	1
UCEC	P-Cadherin →	-0.205	-3.159	.003	.019	3	1
UCEC	Shc_pY317 →	-0.178	-2.459	.015	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Annexin_VII by ACBD4 expression — UCEC

Explore this box plot interactively →