ACBD4

Across TCGA cell cohorts, ACBD4 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ACBD4-associated genes across cancer lineages are OR1E2, G6PC, and OR1E1. Each is linked with ACBD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACBD4-to-partner and partner-to-ACBD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1E2 grouped by ACBD4-low versus ACBD4-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACBD4→partner) and Y-score (partner→ACBD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR1E2 →	+0.093	+6.022	<.001	.001	3	1
SKIN	G6PC →	+0.006	+5.415	<.001	.004	3	1
SKIN	OR1E1 →	+0.692	+4.977	<.001	.007	3	1
LARGE_INTESTINE	PTH →	+0.049	+3.684	<.001	.006	3	1
LARGE_INTESTINE	KLF18 →	+0.009	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR1E2 by ACBD4 expression — SKIN

Explore this box plot interactively →