ACBD3

Across TCGA patient cohorts, ACBD3 mutation is significantly associated with the RNA expression of many other genes, with 2,277 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACBD3-associated genes across cancer lineages are HNRNPH1P2, GAPDHP56, and OPCML-IT1. Each is linked with ACBD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACBD3-to-partner and partner-to-ACBD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HNRNPH1P2 grouped by ACBD3-low versus ACBD3-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACBD3→partner) and Y-score (partner→ACBD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HNRNPH1P2 →	+0.050	+4.452	<.001	.006	3	2
SKCM	GAPDHP56 →	+0.046	+5.594	<.001	.004	3	2
HNSC	OPCML-IT1 →	+0.021	+4.748	.002	.003	3	2
CESC	HNRNPCL3 →	+0.048	+4.551	.006	.004	3	2
UCEC	RNU6-933P →	+0.257	+1.521	.007	.005	3	2
BRCA	MIR3675 →	+0.418	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,277 associations by consensus.

HNRNPH1P2 by ACBD3 expression — HNSC

Explore this box plot interactively →