ACBD3-AS1

Across TCGA pan-cancer cohorts, ACBD3-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated ACBD3-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ACBD3-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ACBD3-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

HNSC, KIRC, and UVM are the cancer types where ACBD3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	IV	0.642	0.377	<.001	49	view →
KIRC	DFS	Tertile	All	0.555	0.712	.001	40	view →
UVM	DFS	Median	III,IV	0.272	0.801	.003	37	view →
MESO	OS	Tertile	III,IV	0.244	0.460	.020	32	view →
UCEC	OS	Quartile	All	0.975	0.877	<.001	32	view →
COAD	DFS	Median	III,IV	0.247	0.593	.002	30	view →
LAML	DFS	Median	All	0.480	0.256	.002	30	view →
LGG	DFS	Median	All	0.773	0.890	<.001	30	view →
ACC	OS	Quartile	All	0.351	0.802	.002	28	view →
ESCA	OS	Tertile	III,IV	0.688	0.349	.002	15	view →
KIRP	OS	Quartile	II,III,IV	0.553	1.000	.010	14	view →
BRCA	DFS	Quartile	IV	0.730	0.174	.016	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

ACBD3-AS1–HNSC (OS)

Open the HNSC breakdown →