ACAT2

Across TCGA cell cohorts, ACAT2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACAT2-associated genes across cancer lineages are CST9L, ZNF804B, and CLEC20A. Each is linked with ACAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACAT2-to-partner and partner-to-ACAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CST9L grouped by ACAT2-low versus ACAT2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAT2→partner) and Y-score (partner→ACAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CST9L →	+0.029	+4.977	<.001	.007	3	1
LARGE_INTESTINE	ZNF804B →	+0.015	+5.415	.001	.004	3	1
LARGE_INTESTINE	CLEC20A →	+0.048	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CST9L by ACAT2 expression — LARGE_INTESTINE

Explore this box plot interactively →