ACAP2

Across TCGA patient cohorts, ACAP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,149 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACAP2-associated proteins across cancer lineages are PAK2, HMCES, and PPP1R2. Each is linked with ACAP2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ACAP2-to-partner and partner-to-ACAP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACAP2 versus PAK2 in OV, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAP2→partner) and Y-score (partner→ACAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PAK2 →	+0.362	+0.722	<.001	<.001	3	8
LSCC	HMCES →	+0.461	+0.624	<.001	<.001	3	5
LSCC	PPP1R2 →	+0.305	+0.746	<.001	<.001	3	5
LSCC	FXR1 →	+0.444	+0.917	<.001	<.001	3	5
LSCC	PCYT1A →	+0.702	+0.877	<.001	<.001	3	5
LSCC	UBXN7 →	+0.639	+1.062	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,149 associations by consensus.

ACAP2 vs PAK2 — OV

Explore this scatter interactively →